Research progress on thymus reconstruction
10.3969/j.issn.1000-484X.2018.03.031
- VernacularTitle:胸腺重建的研究进展
- Author:
Zou-Zou YU
1
;
Li-Huan HU
;
Qian-Lan XU
;
Yin-Hong SONG
Author Information
1. 三峡大学医学院
- Keywords:
Thymic epithelial cell;
Thymus reconstruction;
T lymphocyte regeneration;
Aging
- From:
Chinese Journal of Immunology
2018;34(3):468-471
- CountryChina
- Language:Chinese
-
Abstract:
Thymus,a main organ for T cell development,plays a pivotal role in adaptive immune response and dealing with the threaten from pathogens and tumors.With the deep understanding of the thymus,people have been realizing that the thymus is extremely sensitive to acute and chronic injuries as well as involution with age.Thymus regeneration can recover its function to a certain level.Up to now,these methods including adoptive thymic epithelial progenitor cells immunotherapy,injection of IL-2 and angiogenesis factor and regulation of c-Met signal are able to promote thymus recovery and T cell regeneration.
