Advances in research on autoantibodies of primary sj?gren′s syndrome
10.3969/j.issn.1000-484X.2018.02.030
- VernacularTitle:原发性干燥综合征的自身抗体研究进展
- Author:
Xiao-Wen YU
1
;
Qin WANG
;
Jing FENG
;
Shu-Tong BAI
;
Jin-Kun LIU
;
Hong-Yan GAO
;
Bin WU
Author Information
1. 重庆市中医院中医药基础研究室
- Keywords:
Primary Sj?gren′s syndrome;
Autoantibody;
Diagnosis;
Pathogenesis
- From:
Chinese Journal of Immunology
2018;34(2):301-305
- CountryChina
- Language:Chinese
-
Abstract:
Primary Sj?gren′s syndrome(pSS)is a chronic autoimmune disease which is characterized by exocrine gland dam-age.Studies have found that pSS is associated with a variety of autoantibodies,including anti-Ro/SSA,-La/SSB,-M3R,-α-fodrin,-AD-AMTS13,-NA-14,-IFN-γ,-REG Iα,-MDM2.In this paper,we reviewed the progress of autoantibodies in the diagnosis,disease prediction and pathogenesis of pSS in recent years,so as to provide new ideas for pSS clinical and scientific research.