Research progress on effects of F-actin remodeling on dendritic cell morphology and function
10.3969/j.issn.1000-484X.2018.01.023
- VernacularTitle:F-actin重构对树突状细胞形态和功能影响的研究进展
- Author:
Xian-Mei LIU
1
;
Zhu ZENG
;
Wei-Juan YAO
Author Information
1. 贵州医科大学
- Keywords:
Dendritic cells;
Cytoskeleton;
Filamentous actin;
Morphology;
Antigen presenting;
Migration
- From:
Chinese Journal of Immunology
2018;34(1):117-121,126
- CountryChina
- Language:Chinese
-
Abstract:
Dendritic cells (DCs)are the most potent antigen presenting cells,which play crucial roles in initiating and amplifying both the innate and adaptive immune responses.In DCs' whole life,the dynamics of cytoskeleton is involved in the regulation of their deformation,migration,adhesion,endocytosis and antigen presentation.The cytoskeleton is a complex system and regulated by lots of cytoskeletal proteins.With the research going,our understanding on cytoskeleton system is getting clear.Based on these,we summarized the effects of filamentous actin (F-actin)cytoskeleton remodeling on the morphology and immune functions of DCs.
