Surveillance of antimicrobial resistance in Dongguan Tungwah Hospital during 2016
10.16718/j.1009-7708.2018.01.015
- VernacularTitle:2016年东莞东华医院细菌耐药性监测
- Author:
Shujin XIE
1
;
Zhusheng GUO
;
Jing ZHOU
;
Guiling CHEN
;
Sen FENG
;
Li ZHANG
Author Information
1. 广东省东莞市中山大学附属东华医院检验科
- Keywords:
antimicrobial resistance;
antimicrobial susceptibility testing;
antimicrobial agent
- From:
Chinese Journal of Infection and Chemotherapy
2018;18(1):76-83
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the antimicrobial resistance profile of clinical isolates in Dongguan Tungwah Hospital during 2016.Methods Antimicrobial susceptibility testing was carded out for the clinical isolates collected from Dongguan Tungwah Hospital according to a unified protocol using Kirby-Bauer method or automated systems.Result were analyzed according to CLSI 2016 breakpoints.Results Of the 3 482 clinical isolates,gram positive cocci and gram negative bacilli accounted for 34.4％ (1 199/3 482) and 65.6％ (2 283/3 482),respectively.The prevalence of methicillin-resistant strains was in 28.7％ (86/300) in S.aureus and 77.7％ (300/386) in coagulase-negative Staphylococcus isolates.No staphylococcal strains were found resistant to vancomycin or linezolid.Overall,one E.faecium strain was identified as resistant to vancomycin by instrument method and confirmed by vancomycin E test.The prevalence of ESBLs-producing strains was 59.6％ (337/565) in E.coli and 29.8％ (115/386) in Klebsiella spp.(K.pneumoniae and K.oxytoca).Enterobacteriaceae strains were still highly susceptible to carbapenems.Overall,0.4％ and 0.2％ of the Enterobacteriaceae strains were resistant to imipenem and meropenem,respectively.About 38.3％ and 36.9％ of Acinetobacter strains were resistant to imipenem and meropenem,respectively.Conclusions Surveillance of antimicrobial resistance is most important and valuable for understanding the changing resistant pattern in local hospital and rational selection of antimicrobial agents.More attention should be paid to surveillance of antimicrobial resistance to avoid the spread of drug resistant strains.
