Value of red blood cell distribution width in the prognosis of patients with bloodstream infection
10.16718/j.1009-7708.2018.01.004
- VernacularTitle:红细胞分布宽度对感染患者预后的评估价值
- Author:
Hengmin JIA
1
;
Kai YANG
;
Liang ZHANG
Author Information
1. 安徽医科大学附属省立医院感染管理科
- Keywords:
bacterial infection;
red blood cell distribution width;
intensive care unit;
prognosis
- From:
Chinese Journal of Infection and Chemotherapy
2018;18(1):18-21
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between red blood cell distribution width (RDW) and prognosis in patients with bloodstream infection.Methods A total of 112 patients with positive blood culture were identified from ICU in Anhui Provincial Hospital Affiliated to Anhui Medical University from 2013 to 2015.The clinical data were reviewed and analyzed,including the acute physiology and chronic health assessment Ⅱ (APACHE-Ⅱ) score,RDW,average volume of red blood cells,hemoglobin,C-reactive protein (CRP),procalcitonin (PCT) and serum creatinine.Patients were summarized to compare relevant laboratory tests in terms of survival status.The correlation between RDW and corresponding tests was analyzed by Spearman's correlation.Multivariate logistic regression analysis was used to analyze the independent risk factors of prognosis.The area under the curve (AUC) was calculated by ROC curve to predict the risk of death.Kaplan-Meier survival analysis was used to plot the 30-day survival curve.The relationship between RDW and the risk of death was estimated.Results There was a positive correlation between RDW and CRP,PCT and APACHE Ⅱ score (r=0.225,0.266,0.267,P＜0.05).Logistic regression analysis showed that RDW and APACHE Ⅱ score were independent risk factors for the prognosis of the patients with bloodstream infection.The lower AUC of RDW was 0.634 associated with sensitivity of 0.600,and specificity of 0.641.Conclusions RDW can be used as a sensitive predictor of prognosis in patients with bloodstream infection.
