Neurobiological Effect of Brain-derived Neurotrophic Factor after Spinal Cord Injury(review)
10.3969/j.issn.1006-9771.2018.02.008
- VernacularTitle:脊髓损伤后脑源性神经营养因子神经生物学效应的研究进展
- Author:
Xiang-Zhe LI
1
;
Can WANG
;
Qin-Feng WU
;
Tong WANG
Author Information
1. 苏州科技城医院康复医学中心
- Keywords:
spinal cord injury;
brain-derived neurotrophic factor;
neural repair;
spasticity;
neuropathic pain;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2018;24(2):160-164
- CountryChina
- Language:Chinese
-
Abstract:
Spinal cord injury(SCI)can lead to varying degrees of somatic and autonomic dysfunction and seriously affect the quali-ty of life of patients.The neurobiology and function promotion effects of brain-derived neurotrophic factor(BDNF)after SCI have been extensively studied,including neuroprotection,neuroplasticity and process regulation of neuroinflamma-tion,etc.,as well as functional recovery.However,the adverse effects of BDNF after SCI,such as neuropathic pain and spasticity,were also studied.
