Application of ultrasound targeted microbubble destruction in gene therapy of diabetes mellitus
10.13929/j.1672-8475.201712036
- VernacularTitle:超声靶向破坏微泡在糖尿病基因治疗中的应用
- Author:
Zhiwei ZHENG
1
;
Yun ZHAO
;
Zhaoqi LIU
Author Information
1. 三峡大学医学院,湖北宜昌443002
- Keywords:
Diabetes mellitus;
Microbubbles;
Gene therapy
- From:
Chinese Journal of Interventional Imaging and Therapy
2018;15(6):383-386
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes mellitus is a metabolic disease characterized by hyperglycemia,resulting in chronic damage and dysfunction of many organs,such as the eyes,kidneys,heart,blood vessels,nerves,etc.,which increase the difficulty of treatment for diabetes.In recent years,gene therapy for diabetes mellitus has become a hot topic.Ultrasound targeted microbubble destruction (UTMD) has the advantage of safety,good repeatability and tissue targeting,and has become a potential strategy for gene delivery.The related study progresses of UTMD in gene therapy of diabetes mellitus were reviewed in this article.