Combined biliary drainage for treatment of malignant obstructive jaundice caused by Bismuth Ⅳ Klatskin tumors
10.13929/j.1672-8475.201802005
- VernacularTitle:复合胆道引流术治疗Bismuth Ⅳ型Klatskin肿瘤所致恶性梗阻性黄疸
- Author:
Jian WEI
1
;
Honglu LI
;
Jiang GUO
;
Changqing LI
Author Information
1. 首都医科大学附属北京地坛医院肿瘤介入科
- Keywords:
Jaundice,obstructive;
Drainage;
Cholangiocarcinoma;
Treatment outcome
- From:
Chinese Journal of Interventional Imaging and Therapy
2018;15(6):337-340
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of two kinds of combined biliary drainage in the treatment of malignant obstructive jaundice (MOJ) caused by Bismuth Ⅳ Klatskin tumor.Methods Data of 46 MOJ patients caused by Bismuth Ⅳ Klatskin tumor who received combined biliary drainage were retrospectively analyzed.The patients were divided into bilateral percutaneous transhepatic biliary drainage (PTBD) group (n =19) and endoscopic nasobiliary drainage (ENBD) combined with unilateral PTBD group (n=27).Internal and external drainage of the biliary tract were performed.The clinical effect of drainage,survival time and complication rate after drainage were compared between the two groups.Results The technical success rates of drainage in both groups were 100％.There was no statistically significant difference in the effective rate of drainage between the two groups (89.47％ [17/19] vs 92.59％ [25/27];x2=0.02,P=0.831).Compared with ENBD combined with unilateral PTBD group,patients in bilateral PTBD group showed longer survival time ([318.37±167.39] days vs [267.57±145.21] days;t=7.31,P=0.007) and lower complication rate (10.52 ％[2/19] vs 14.81％ [4/27];x2 =1.92,P=0.028) after drainage.Conclusion Combined biliary drainage techniques can effectively alleviate MOJ caused by Bismuth 1Ⅳ Klatskin tumors and improve liver function.Bilateral PTBD is more beneficial to prolong patients;survival time than ENBD combined PTBD.
