Impact of local lipiodol deposition in liver on necrotic area after microwave ablation in miniature pigs
10.13929/j.1672-8475.201711056
- VernacularTitle:小型猪肝脏局部碘化油微环境对微波消融灶的影响
- Author:
Tingting BAO
1
;
Jian WANG
;
Zhenzhen LI
;
Shoujin CAO
;
Yang ZHANG
;
Letao LIN
;
Li SONG
;
Xiaoqiang TONG
;
Yinghua ZOU
Author Information
1. 北京大学第一医院介入血管外科
- Keywords:
Iodized oil;
Tomography,X-ray computed;
Liver neoplasms;
Chemoembolization,therapeutic;
Heat sink effect;
Microwave ablation
- From:
Chinese Journal of Interventional Imaging and Therapy
2018;15(5):291-294
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the impact of local lipiodol deposition in liver of miniature pigs on the shape and size of the necrotic area after microwave ablation (MWA).Methods Ten healthy miniature pigs were selected and equally divided into experimental group and control group (each n=5).In experimental group,transcatheter hepatic arterial embolization with lipiodol was done before microwave ablation,while only standard microwave ablation was performed in control group.Immediate post-ablation CT images were obtained.Long-axis diameter (LAD),short-axis diameter (SAD),sphericity index (SI=SAD/LAD) and volume of ablation zone were calculated.The size and shape of the ablated areas were compared between two groups.Results The mean LAD,SAD,SI and volume of ablation zone in experimental group ([4.21 ± 0.52]cm,[2.87±0.38]cm,0.69±0.10,[18.72±6.08]cm3) were larger than those in control group ([3.71±0.42]cm,[2.19±0.42]cm,0.60±0.09,[9.44±2.29] cm3;all P＜0.05).Conclusion Local deposition of lipiodol in liver parenchyma of miniature pigs can help to produce larger and rounder necrosis in the ablation zone.
