Efficacy and safety of HIFU ablation for uterine fibroids in patients with abdominal surgical scars in acoustic pathway causing acoustic attenuation width <10 mm
10.13929/j.1672-8475.201708039
- VernacularTitle:HIFU治疗超声衰减宽度<10mm声通道腹壁瘢痕子宫肌瘤患者的有效性及安全性
- Author:
Na YIN
1
;
Ling WANG
;
Liang HU
;
Chao YANG
;
Zhibo XIAO
;
Jinyun CHEN
;
Zhibiao WANG
Author Information
1. 重庆医科大学生物医学工程学院省部共建国家重点实验室培育基地—重庆市超声医学工程重点实验室重庆市生物医学工程学重点实验室重庆市微无创医学协同创新中心
- Keywords:
Leiomyoma;
Uterus;
Abdominal wall;
Cicatrix;
High-intensity focused ultrasound ablation
- From:
Chinese Journal of Interventional Imaging and Therapy
2018;15(4):221-225
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic efficacy and safety of HIFU ablation for uterine fibroids in patients with abdominal surgical scars in acoustic pathway causing acoustic attenuation width <10 mm.Methods Totally 861 patients with uterine fibroids were referred for HIFU treatment and underwent contrast-enhanced MR scans before and after HIFU ablation.Among all patients,202 had abdominal surgical scars causing width <10 mm acoustic attenuation (abdominal scars group) and 659 had no abdominal surgical scars (without abdominal scars group).The outcomes,intra-operative adverse reactions and post-operative complications between the two groups were compared.Results HIFU ablation was successfully performed in all patients.The volume ablation rate was (80.31 ± 18.16)% in abdominal scars group and (79.60±17.57)% in without abdominal scars group (P=0.620).The rate of ‘hot'skin sensation during HIFU procedure in abdominal scars group (52.97% [107/202]) was higher than that in without abdominal scars group (41.58% [274/ 659];P=0.004).Anterior abdominal wall edema was found in 40 cases (40/202,19.80%) in abdominal scars group and 98 cases (98/659,14.87%) in without abdominal scars group on post-operation MRI (P= 0.095).Conclusion Prior abdominal surgical scars in acoustic pathway causing width <10 mm acoustic attenuation has not significantly influence on the efficacy and safety of HIFU treatment for uterine fibroid.