Impact of antiplatelet therapy on risk of hemorrhage after percutaneous nephrostomy

VernacularTitle:抗血小板治疗对经皮肾穿刺造瘘术术后出血风险的影响
Author: Qinzong GAO ¹ ; Zhengyu JIN ; Zhiwei WANG ; Jie PAN ; Xiaoguang LI ; Haifeng SHI ; Xiaobo ZHANG ; Wei LIU ; Ning YANG
Author Information

1. 中国医学科学院北京协和医学院
Keywords: Nephrostomy,percutaneous; Hemorrhage; Antiplatelet
From: Chinese Journal of Interventional Imaging and Therapy 2018;15(2):65-68
CountryChina
Language:Chinese
Abstract: Objective To explore the impact of antiplatelet agents on the occurrence of hemorrhage after percutaneous nephrostomy (PCN).Methods Totally 197 patients (244 kidneys) underwent PCN were enrolled and divided into postoperative hemorrhage group and without postoperative hemorrhage group.The possible factors of the postoperative hemorrhage were analyzed.Results Post-operative hemorrhage occurred in 23 patients with 27 kidneys (27/244,11.07％).Univariate analysis showed that except for antiplatelet drugs,the other factors had no statistical difference between the two groups (P＞0.05).Logistic regression analysis showed that taking dual-antiplatelet was the risk factor of hemorrhage after PCN (OR=12.381,P =0.002).Conclusion Single aspirin therapy can not increase the risk of hemorrhage after PCN,while taking dual-antiplatelet might increase the risk of hemorrhage.Normal clotting function is also a guarantee of preventing hemorrhage after PCN.