Outcome of percutaneous ultrasound-guided radiofrequency ablation for liver metastases from gastric cancer
10.13929/j.1672-8475.201707019
- VernacularTitle:经皮超声引导下射频消融治疗胃癌肝转移疗效分析
- Author:
Binbin JIANG
1
;
Zhongyi ZHANG
;
Kun YAN
;
Wei YANG
;
Wei WU
;
Lung-Chieh LEE
;
Minhua CHEN
Author Information
1. 北京大学肿瘤医院暨北京市肿瘤防治研究所超声科恶性肿瘤发病机制及转化研究教育部重点实验室
- Keywords:
Stomach neoplasms;
Catheter ablation;
Neoplasm metastasis;
Prognosis
- From:
Chinese Journal of Interventional Imaging and Therapy
2018;15(1):24-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and prognostic factors of percutaneous ultrasound-guided radiofrequency ablation (RFA) for liver metastases from gastric cancer.Methods Clinical and imaging data of 55 patients with liver metastasis from gastric cancer who underwent percutenous ultrasound-guided RFA were retrospectively analyzed,and the overall survival rates and prognostic factors were assessed.Results The overall survival rates of 1-,2-,3-and 5-year was 70.45%,42.90%,20.32% and 10.16%,respectively.The ablation rate was 94.12% (96/102) 1 month after RFA,and the local recurrent rate was 15.69% (16/102),the new metastasis rate was 52.73% (29/55).Age (P=0.015),tumor number (P=0.011),extrahepatic metastasis before RFA (P=0.026) and chemotherapy after RFA (P=0.031) were significantly prognostic factors.Age (P=0.033),tumor number (P=0.004) as well as chemotherapy after RFA (P=0.001) were independent prognostic factors.The severe complication rate was 1.82% (1/55),while no treatment-related death occurred.Conclusion Percutaneous ultrasound-guided RFA is a safe and effective therapeutic option for liver metastases from gastric cancer.Age,tumor number,chemotherapy after RFA are independent prognostic factors.