Perioperative sustained renal replacement therapy for percutaneous coronary intervention i patients with severe acute myocardial infarction
10.3969/j.issn.1004-8812.2018.02.009
- VernacularTitle:重症急性心肌梗死患者经皮冠状动脉介入治疗围术期持续肾替代的疗效分析
- Author:
Han-Xiang GAO
1
;
Ming BAI
;
Cun-Rui ZHAO
;
Jing ZHAO
;
Chen-Liang PAN
;
Zheng ZHANG
Author Information
1. 兰州大学第一医院心血管内科
- Keywords:
Continuous renal replacement therapy;
Acute myocardial infarction;
Percutaneous coronary intervention
- From:
Chinese Journal of Interventional Cardiology
2018;26(2):106-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the safety and efficacy of continuous renal replacement therapy (CRRT) during percutaneous coronary intervention (PCI) in patients with severe acute myocardial infarction (AMI). Methods A total of 945 patients with AMI who were hospitalized in the CCU of the First Hospital of Lanzhou University from January 2016 to December 2017 were retrospectively analyzed and 21 patients had undergone perioperative CRRT during percutaneous coronary intervention. Baseline clinical characteristics of the AMI patients were evaluated before and after CRRT treatment. The changes in heart function, renal function, liver function and other parameters were evaluated. Results The heart rate of patients receiving CRRT was significantly lower at 24h and 48h after CRRT than that of before treatment (P=0.038). Decrease in mean systolic blood pressure and diastolic blood pressure was observed af ter CRRT treatment without statistical significance (P>0.05). Proportion of patients with Killip class I ~ II heart function increased significantly after CRRT[23.8%(5/21)vs. 57.1%(12/21),P=0.001]. Amelioration in urea nitrogen, creatinine, aspartate aminotransferase, glutamic pyruvic transaminase and total bilirubin were found at 24h and 48h after CRRT treatment compared to pre-CRRT levels (P<0.05). Conclusions Perioperative CRRT is safe and effective for patients with severe AMI.
