Analysis of characteristics and risk factors related to adult patients of primary immune thrombocytopenia with infection
10.3760/cma.j.issn.1008-6706.2018.22.013
- VernacularTitle:成年人原发免疫性血小板减少症继发感染166例特征及危险因素分析
- Author:
Weiying FENG
1
;
Hongqiang LUO
;
Yonggen ZHONG
;
Ting LUO
Author Information
1. 绍兴市人民医院血液科
- Keywords:
Thrombocytopenia;
Infection;
Megakaryocytes;
Diabetes mellitus;
Glucocorticoids;
Risk factors;
Factor analysis;
statistical
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(22):2907-2911
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors related to adult patients of primary immune thrombocytopenia with infection,so as to provide basis for control and prevention of infection. Methods From January 2015 to December 2017,the clinical data of 166 adult patients of primary immune thrombocytopenia in the People's Hospital of Shaoxing-were retrospectively analyzed. Statistical analysis was performed by SPSS21. 0 statistical software. Results The infec-tion rate was 24. 70％ (41 / 166). The risk factors related to infection were age(OR = 1. 290,P = 0. 011),the number of bone marrow megakaryocytes(OR = 1. 220,P = 0. 022),diabetes(OR = 2. 163,P < 0. 001) and glucocorticoid (OR =2. 203,P <0. 001). There were 45 strains of pathogenic bacteria detected in 41 patients,gram negative bacteria accounted for 51. 11％ (23 / 45),gram positive bacteria accounted for 44. 44％ (20 / 45),and fungi accounted for 4. 44％ (2 / 45). Conclusion A variety of factors are related to infection in adult primary immune thrombocytopenia patients. It is necessary to take effective prevention measure,which will help reduce the incidence of infection.
