Progress in the pathogenesis of hepatic fibrosis
10.3760/cma.j.issn.1008-6706.2018.19.037
- VernacularTitle:肝纤维化的发生机制及其研究进展
- Author:
Wenshan YANG
1
;
Wu LI
Author Information
1. 昆明医科大学第一附属医院感染科
- Keywords:
Liver cirrhosis;
Hepatic stellate cell;
Extracellular matrix;
Cytokines;
Review
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(19):2582-2584
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic fibrosis is an important part of development of chronic liver inflammation further to cirrhosis,liver cancer.The formation of hepatic fibrosis is a complex pathological process involving multiple cells and multiple factors.The progress of hepatic stellate cells(HSC),extracellular matrix(ECM),cytokines and autophagy,sphingosine kinase 1(Spk1)in the pathogenesis of hepatic fibrosis is reviewed in this study.
