Effect of sequential therapy of linezolid and teicoplanin for the treatment of the severe pneumonia induced by gram-positive coccus
10.3760/cma.j.issn.1008-6706.2018.16.006
- VernacularTitle:利奈唑胺与替考拉宁序贯治疗革兰阳性球菌重症肺炎的疗效观察
- Author:
Xuelian CHEN
1
;
Ying XIA
;
Qingfeng WANG
Author Information
1. 舟山市中医院ICU
- Keywords:
Pneumonia;
Gram-positive cocci;
Linezolid;
Teicoplanin;
Intensive care
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(16):2061-2063
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of sequential therapy of linezolid and teicoplanin for the treatment of the severe pneumonia induced by gram-positive coccus.Methods From September 2014 to August 2017,0 cases of severe pneumonia patients in the Traditional Chinese Medicine Hospital of Zhoushan were gram positive coccus,tumbled to rina amine for patients treated with intravenous drip,the course of treatment was 7 days,and then intravenous drip their stead better treatment,treatment for 7 days,the clinical situation of patients before and after treatment respectively,the characteristics of signs and adverse reactions were analyzed.Results Among the 51 cases (63.75%),19 cases (23.75%),8 cases (10.00%),and 2 cases (2.5%),the total effective rate was 87.5 %.In the distribution and clearance rate of pathogenic bacteria,the bacterial clearance rate of liniazolamide and the replacement of gram-positive coccus pneumoniae was 87.50%.There was no other adverse reaction.Conclusion Sequential therapy of linezolid and teicoplanin for the treatment of the severe pneumonia induced by gram-positive coccus has several good effects,high clearance rate of pathogenic bacteria,good security.