Age specific serum anti-Mullerian hormone levels in 1,298 Korean women with regular menstruation.
10.5653/cerm.2011.38.2.93
- Author:
Ji Hee YOO
1
;
Hye Ok KIM
;
Sun Wha CHA
;
Chan Woo PARK
;
Kwang Moon YANG
;
In Ok SONG
;
Mi Kyoung KOONG
;
Inn Soo KANG
Author Information
1. Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea. ok58163@hanmail.net
- Publication Type:Original Article
- Keywords:
Anti-Mullerian Hormone;
Ovarian Reserve;
Korean;
Human
- MeSH:
Aged;
Anti-Mullerian Hormone;
Female;
Humans;
Menstrual Cycle;
Menstruation;
Reference Values
- From:Clinical and Experimental Reproductive Medicine
2011;38(2):93-97
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To determine the age specific serum anti-Mullerian hormone (AMH) reference values in Korean women with regular menstruation. METHODS: Between May, 2010 and January, 2011, the serum AMH levels were evaluated in a total of 1,298 women who have regular menstrual cycles aged between 20 and 50 years. Women were classified into 6 categories by age: 20-31 years, 32-34 years, 35-37 years, 38-40 years, 41-43 years, above 43 years. Measurement of serum AMH was measured by commercial enzyme-linked immunoassay. RESULTS: The serum AMH levels correlated negatively with age. The median AMH level of each age group was 4.20 ng/mL, 3.70 ng/mL, 2.60 ng/mL, 1.50 ng/mL, 1.30 ng/mL, and 0.60 ng/mL, respectively. The AMH values in the lower 5th percentile of each age group were 1.19 ng/mL, 0.60 ng/mL, 0.42 ng/mL, 0.27 ng/mL, 0.14 ng/mL, and 0.10 ng/mL, respectively. CONCLUSION: This study determined reference values of serum AMH in Korean women with regular menstruation. These values can be applied to clinical evaluation and treatment of infertile women.