Clinical characteristics and prognosis of cerebral infarction with metabolic syndrome
10.3760/cma.j.issn.1008-6706.2018.14.015
- VernacularTitle:脑梗死合并代谢综合征的临床特点与预后研究
- Author:
Wenmin WANG
1
;
Yuemei LIU
;
Hengsheng HOU
Author Information
1. 中山市南朗医院内科
- Keywords:
Infarction,middle artery;
Metabolic syndrome X;
Hyperglycemia;
Hypertension;
Dyslidemlias;
Prognosis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(14):1829-1832
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical characteristics and prognosis of cerebral infarction combined with metabolic syndrome.Methods From July 1,2015 to March 31,2017,250 patients with cerebral infarction combined with metabolic syndrome in four comprehensive hospital in Zhongshan city were studied.The blood pressure,blood lipid,blood sugar,waist circumference,neurological deficit and disability were analyzed before and after treatment. Meanwhile,the neurological function and disability degree of blood pressure,blood lipid,blood sugar,waist circumfer-ence and non qualified patients were compared.Results After treatment for two weeks,three months and six months, the systolic blood pressure [(132.21±11.25)mmHg,(126.37 ±10.26)mmHg,(122.29 ±11.12)mmHg], diastolic blood pressure [(90.12 ±5.21)mmHg,(84.16 ±4.11)mmHg,(82.23 ±3.10)mmHg],triglycerides [(1.81±0.24)mmol/L,(1.64 ±0.35)mmol/L,(1.51±0.25)mmol/L],high －density lipoprotein cholesterol [(1.01±0.31)mmol/L,(1.08 ±0.36 )mmol/L,(1.19 ±0.34 )mmol/L],fasting plasma glucose [(6.26 ± 0.56)mmol/L,(6.10 ±0.34)mmol/L,(5.59 ±0.34)mmol/L],two－hour postprandial blood glucose [(8.36 ± 1.12)mmol/L,(7.34 ±1.10)mmol/L,(7.05 ±0.26)mmol/L],neurological deficit scores [(31.26 ±1.16)points, (26.58 ±1.05)points,(21.10 ±0.34)points],disability scores [(3.26 ±0.34)points,(2.10 ±0.25)points, (0.59 ±0.20)points]were better than those before treatment (F＝5.10,5.23,5.45,4.89,4.21,4.20,4.26,4.58, P＝0.02,0.04,0.02,0.03,0.01,0.02,0.02,0.03).After treatment for three months and six months,the waist circ-umference [(82.21±5.10)cm,(81.23 ±4.16)cm]were less than before treatment (F＝5.26,P＝0.03).After treatment,the compliance rate of blood pressure,blood lipids,blood glucose,waist circumference was 79.20%,and the not met rate was 20.80%.The neurological deficit score [(17.25 ±1.26)points]and disability score[(0.34 ± 0.12)points]were lower than those who did not meet standard(t＝29.64,17.44,P＝0.01,0.01).Conclusion High blood pressure,high blood lipid and high blood sugar are the main clinical characteristics of patients with cerebral infarction combined with metabolic syndrome,and relieving the symptoms of＂three high＂can improve the prognosis.
