Clinical study of autologous bone marrow mesenchymal stem cells in repairing osteonecrosis ( stage Ⅰ and Ⅱ)

VernacularTitle:采用自体骨髓间充质干细胞修复股骨头坏死(Ⅰ、Ⅱ期)的临床研究
Author: Xudong HUANG ¹ ; Junwei ZHANG ; Di CAI ; Feng ZHANG ; Guihao WANG ; Deling KONG
Author Information

1. 淮南东方医院集团总院介入科
Keywords: Marrow mesenchymal stem cells transplantation; Femur head necrosis
From: Chinese Journal of Primary Medicine and Pharmacy 2018;25(8):1059-1062,后插3
CountryChina
Language:Chinese
Abstract: Objective To study the effect of autologous bone marrow mesenchymal stem cells in the treatment of osteonecrosis .Methods 56 cases of osteonecrosis of femeral head ( ONFH) were treated with autologous bone marrow mesenchymal stem cells .DSA observed neovascularization after transplantation ,morphological changes of femoral head were observed by imaging method .Results Of the 30 patients who underwent autologous bone marrow stem cell transplantation,86.6％had resuscitation of hip pain,23.3％ had improved hip function,and 85.7％ had walking distance .Examination showed that the arterial artery was significantly increased before transplantation , thickening,faster blood flow.The femoral head area of the bone was significantly improved (100.0％) after 12 -24 months.Conclusion The method of transplantation of bone marrow mesenchymal stem cells is simple ,safe and effective.It is effective for stage I and II of the avascular necrosis of the femoral head .