Effect of heat phlegm and nourishing Yin combined with glucocorticoids in the treatment of refractory Mycoplasma pneumoniae pneumonia in children
10.3760/cma.j.issn.1008-6706.2018.08.021
- VernacularTitle:清热消痰养阴方联合糖皮质激素治疗儿童难治性肺炎支原体肺炎的疗效研究
- Author:
Baozhen ZHANG
1
;
Lihe WANG
Author Information
1. 运城市中心医院儿科
- Keywords:
Heat phlegm and nourishing yin;
Glucocorticoids;
Pneumonia,mycoplasma
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(8):1030-1033
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of phlegm and nourishing Yin combined with glucocorticoids in the treatment of refractory Mycoplasma pneumoniae pneumonia in children .Methods 134 children with Mycoplasma pneumonia were divided into control group and observation group according to the random number , 67 cases in each group .The control group were given hydrocortisone ,and the observation group received phlegm and nourishing Yin combined with glucocorticoid .After intervention ,the clinical data and the improvement of the clinical symptoms of the two groups were compared .Results There was no statistically significant difference in antipyretic time between the two groups(P>0.05).The time of cough relief,the absorption time of lung rales,the disappearance time of pleural effusion of the observation group were (3.61 ±1.13) d,(6.52 ±1.90) d and (7.02 ±2.10) d, respectively,which were significantly shorter than those of the control group [(4.89 ±2.18)d,t=2.920,P=0.021;(8.24 ±2.75)d,t=3.108,P=0.000;(9.26 ±2.38)d,t=5.027,P=0.000].There were no statistically signifi-cant differences in the total white blood cell count ,C-reactive protein and erythrocyte sedimentation rate between the two groups(all P>0.05).The percentage of lymphocytes in the observation group [(55.25 ±4.91)％] was signifi-cantly higher than that in the control group [(50.16 ±4.83)％,t=2.597,P=0.037].The effective treatment rate in the observation group was 97.01％,which was significantly higher than 83.58％in the control group (χ26.849,P=0.009).Conclusion Heat phlegm and nourishing Yin combined with glucocorticoid can not only effectively improve the patients'clinical symptoms , improve the proportion of lymphocyte , but also can improve the overall efficacy of children,it is worthy of clinical promotion .
