Analysis of therapeutic effect of sodium hyaluronate intra-articular injection combined with oral Yanghe decoction in the treatment of knee osteoarthritis
10.3760/cma.j.issn.1008-6706.2018.08.007
- VernacularTitle:玻璃酸钠关节腔注射配合口服阳和汤治疗膝骨关节炎的疗效分析
- Author:
Yina ZHAO
1
;
Jiangtao ZHOU
Author Information
1. 浙江中医药大学附属温州市中医院药剂科
- Keywords:
Osteoarthritis,knee;
Joint capsule;
Sodium hyaluronate;
Medicine,Chinese traditional
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(8):976-980
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the curative effect of sodium hyaluronate intraperitoneal injection combined with oral Yanghe decoction in the treatment of knee osteoarthritis .Methods 80 patients with knee osteoar-thritis were randomly divided into two groups ,40 cases in each group .The control group was given intra -articular injection of sodium hyaluronate ,and the study group was treated with Yanghe decoction in addition .The TCM symptom score , knee joint index , overall treatment effect and quality of life were compared between the two groups .Results The total score of TCM symptoms after treatment in the study group was (7.08 ±1.18)points,which was significantly lower than (10.42 ±2.01)points in the control group(t=9.063,P<0.01).The VAS score and WOMAC score after treatment in the study group were (1.48 ±0.59)points,(19.10 ±3.08)points,respectively,which were significantly lower than (3.70 ±1.12)points and (23.40 ±3.56)points in the control group (t=11.091,5.777,all P<0.01). The HSS score after treatment in the study group was (83.04 ±10.49) points,which was significantly higher than (71.81 ±9.67)points in the control group(t =4.978,P<0.01).The physiological function,physical function, physical pain,mental health and energy scores after 6 months treatment in the study group were significantly higher than those in the control group (t=5.190,8.535,4.569,3.266,6.694,all P<0.01).The effective rate and total effective rate of the study group were 72.5％and 95.0％,respectively,which were significantly higher than those of the control group(50.0％,77.5％),the differences were statistically significant (χ2 =4.266,5.165,all P<0.05). Conclusion Sodium hyaluronate injection combined with oral Yanghe decoction is effective in the treatment of knee osteoarthritis.
