Correlation analysis of blood lead and zinc with tic disorders in children

VernacularTitle:血铅、锌水平与儿童抽动障碍的相关性分析
Author: Xueying ZHU ¹ ; Feng YU ; Chunfa MAO
Author Information

1. 兰溪市人民医院儿科
Keywords: Tic disorders; Lead; Zinc; Child
From: Chinese Journal of Primary Medicine and Pharmacy 2018;25(7):850-853
CountryChina
Language:Chinese
Abstract: Objective To analyze the correlation between blood lead,zinc levels and tic disorders(TD) in children.Methods One hundred and fourteen children with TD were chosen as observation group,and 100 healthy children were chosen as control group.The serum levels of lead and zinc were compared between the two groups,and the correlation between blood lead,zinc levels and TD was analyzed.Results The serum level of blood lead in the observation group was (70.8 ± 14.9) μg/L,which was higher than (50.9 ± 13.8),μg/L in the control group,the difference was statistically significant(t =4.932,P ＜ 0.05).The serum level of blood zinc in the observation group was (461.4 ±33.2)μg/L,which was lower than (501.5 ± 34.1)μg/L in the control group,the difference was statistically significant(t =5.217,P ＜ 0.05).The serum level of blood lead ≥60μg/L and the serum level of blood zinc ＜470μ g/L were significantly related with TD(OR =2.192,2.012,all P ＜ 0.05).Conclusion The blood lead and zinc levels are significantly correlated with TD in children.