Clinical observation on efficacy of Ramulus Cinnamomi, Poria capsules combined with mifepristone in the treatment of hysteromyoma
10.3760/cma.j.issn.1008-6706.2018.06.017
- VernacularTitle:桂枝茯苓胶囊联合小剂量米非司酮治疗子宫肌瘤的疗效分析
- Author:
Risheng WANG
1
;
Ping ZHOU
Author Information
1. 安徽理工大学
- Keywords:
Uterine neoplasms;
Cassia tuckahoe capsule;
Mifepristone
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(6):745-748
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy of Ramulus Cinnamomi , Poria capsules combined with mifepristone in the treatment of hysteromyoma .Methods 60 patients with hysteromyoma were treated with drugs ,and according to the outpatient number they were randomly divided into three groups .Ⅰgroup ( n=20) were orally given mifepristone in a dosage of 12.5mg once daily for three months.Ⅱgroup (n=20) were orally given Cassia Tuckahoe Capsule for three months ,and Ⅲ group ( n=20 ) were orally given Cassia Tuckahoe Capsule for three months after given mifepristone in a dosage of 2.5mg once daily for one month.The size of hysteromyoma,FSH,LH,E2 and P were detected before and after treatment .The changes of clinical symptoms and adverse drug reactions were observed . Results The size of hysteromyoma of Ⅰ group and Ⅲ group [(2.41 ±1.03)cm3,(2.69 ±0.97)cm3]reduced significantly(P<0.05).FSH,LH,E2 and P in blood of Ⅰgroup reduced significantly(P<0.05),which inⅡgroup and Ⅲ group had no statistically significant differences between before and after treatment ( all P >0.05 ) . Conclusion Mifepristone combined with cassia tuckahoe capsule in treatment of patients with hysteromyoma is better than those only using mifepristone or cassia tuckahoe capsule .This combination therapy is indicated for preoperative medication or perimenopausal patients for conservative treatment of hysteromyoma .
