Clinical effect of ethinyl estradiol cyproterone tablets combined with ovulation induction in the treatment of polycystic ovary syndrome infertility
10.3760/cma.j.issn.1008-6706.2018.04.027
- VernacularTitle:炔雌醇环丙孕酮片联合促排卵法治疗多囊卵巢综合征不孕的临床疗效分析
- Author:
Shasha PAN
1
;
Yunyun ZHANG
;
Lianju YU
Author Information
1. 315600,浙江省宁海县第一医院妇产科
- Keywords:
Polycystic ovary syndrome;
Infertility,female;
Ethinyl estradiol;
Cyproterone
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(4):507-511
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical effect of ethinyl estradiol cyproterone tablets ( Diane -35 ) combined with ovulation induction in the treatment of polycystic ovary syndrome infertility .Methods 70 patients with polycystic ovary syndrome were enrolled , and they were randomly divided into two groups according to the random number table of the computer ,35 cases in each group .The control group was treated with Diane -35,the observation group was given ovulation induction .The clinical parameters ,vaginal ultrasound results ,cycle ovulation rate ,pregnancy rate,adverse reaction rate and quality of life were compared between the two groups .Results There were no statistically significant differences in uterine volume , intima thickness , bilateral ovarian volume and bilateral follicle number between the two groups after treatment (t=0.055,0.308,0.991,0.435,0.473,0.248,all P>0.05).The cycle ovulation rate of the observation group was significantly higher than that of the control group (80.88％ vs. 54.05％,χ2 =8.451,P<0.01).The shape,color,thought and energy score of the observation group were significantly higher than those of the control group (t=4.819,3.519,4.735,6.804,all P<0.01).The pregnancy rate of the observation group was significantly higher than that of the control group (25.71％vs.5.71％,χ2 =5.285,P<0.05). Conclusion Diane-35 combined with ovulation induction in the treatment of polycystic ovary syndrome infertility has significant clinical efficacy .
