Clinical characteristics and risk factors of multi -drug resistant bacterial infection in diabetic patients
10.3760/cma.j.issn.1008-6706.2018.04.018
- VernacularTitle:糖尿病足患者发生多耐药菌感染的临床特点及危险因素分析
- Author:
Jun LIANG
1
;
Xiuhua JING
;
Guanming CHEN
Author Information
1. 济南市第二人民医院内科
- Keywords:
Diabetic foot;
Infection;
Ulcer;
Pathogenic bacteria;
Factor analysis,statistical
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(4):474-477
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics and risk factors of multiple drug -resistant bacteria infection in patients with diabetic foot .Methods The clinical data of 60 patients with diabetic foot were retrospectively analyzed , including diabetic foot infected ( positive group ) and uninfected multiple drug -resistant bacteria(negative group),30 cases in each group.Application of SPSS 17.0 statistical software for infection and clinical characteristics of the single factor analysis , through the Logistics regression analyzed the risk factors of infection . Results A total of 130 strains bacteria were isolated in the positive group ,of which more than 64 strains of drug-resistant bacteria,the detection rate was 49.23％;The top three for staphylococcus aureus (60.00％),enterobacter (53.33％) and verdigris pseudomonas (31.57％).Single factor analysis results showed that age , hypertension between the two groups had no statistically significant differences (all P>0.05);Positive group in the use of antibiotics prior to admission time,ulcerated area,etc.,compared with the negative group the differences were statistically significant (t=1.812, -7.268,all P <0.05).Multiple factors analysis showed that admission ,antibiotics,ulcerated area, osteomyelitis were risk factors of positive infection in patients .Conclusion The risk factor resulted in diabetic foot patients infected multiple drug -resistant bacteria is more ,and the amputation rate of patients with infection group is obviously higher than that of patients who are not infected ,to ensure that the prognosis of patients with diabetic foot level,should strengthen the control of multiple drug -resistant bacteria infection ,thus to better achieve treatment goals .
