Influence of laparoscopic hysteromyomectomy and hysterectomy on ovarian function in patients with uterine fibroids
10.3760/cma.j.issn.1008-6706.2018.03.021
- VernacularTitle:子宫肌瘤剔除术与子宫切除术对子宫肌瘤患者卵巢功能影响的对照评价
- Author:
Yan XING
1
;
Lining CUI
Author Information
1. 宁波市第一医院妇科
- Keywords:
Laparoscopic hysteromyomectomy;
Hysterectomy;
Leiomyoma;
Ovarian function
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(3):348-351
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of laparoscopic hysteromyomectomy ( LSHM) and hysterectomy ( TH) on ovarian function in patients with uterine fibroids ( UF) .Methods 96 UF patients with accepted surgery in our hospital were selected .The patients were randomly divided into observation group and control group by random number table method ,48 cases in each group .LSHM was used for surgery in the observation group ,while the control group accepted TH surgery.E2,AMH,FSH and LH levels before and after surgery,the operation time,intraoperative blood loss,flatus time and average length of stay ,as well as proportion of perimenopausal symptoms in the two groups were recorded and compared .Results The operation time ,intraoperative blood loss ,flatus time and average length of stay in the observation group were (65.6 ±13.2)min,(82.4 ±6.2)mL,(20.4 ±4.6)h and (5.2 ±1.2)d,respec-tively,which in the control group were (76.5 ±15.6)min,(118.6 ±8.9)mL,(34.2 ±5.4)h and (8.3 ±1.2)d,the differences were statistically significant (t=3.695,P=0.00;t=23.120,P=0.00;t=13.482,P=0.00;t=12.650, P=0.00).The differences of E2,FSH,LH and AMH levels before surgery were not statistically significant (all P>0.05).After surgery,the E2 and AMH levels were significantly higher in the observation group (t=22.630,P=0.00;t=5.910,P=0.00),and FSH and LH levels were significantly lower in the observation group (t=6.853,P=0.00;t=7.024,P=0.00).The incidence rate of perimenopausal symptoms in observation group was 8.3％(4/48),which in the control group was 29.2％ (14/48),the difference was statistically significant (χ2 =6.838,P =0.00). Conclusion LSHM is helpful to protect UF patients'ovarian function ,with faster postoperative recovery ,and deserves further promotion in clinical practice .
