Clinical observation of venenum bufonis combined with antibiotics in the treatment of bacterial liver abscess
10.3760/cma.j.issn.1008-6706.2018.03.009
- VernacularTitle:蟾酥注射液联合抗生素治疗细菌性肝脓肿的临床观察
- Author:
Jiezhong YU
1
;
Huiqing WANG
;
Jiao LI
;
Cungen MA
Author Information
1. 大同大学脑科研究所
- Keywords:
Liver abscess,pyogenic;
Bacteria;
Venenum bufonis;
Anti-bacterial agents
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(3):302-305
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effect of venenum bufonis combined with antibiotics in the treatment of bacterial liver abscess .Methods 60 patients with bacterial liver abscess were enrolled ,and all patients took percutaneous transhepatic puncture guided by ultrasound .They were randomly divided into two groups according to the digital table ,30 cases in each group .The control group received antibiotics treatment ,and the treatment group received venenum bufonis plus antibiotics intravenous drip ,once daily ,one course of treatment lasted seven days .The body temperature , blood routine , procalcitonin and other project changes of the two groups were detected .Results Compared with the control group,the effective rate of the treatment group was higher (96.7％ vs.80.0％,χ2 =4.043,P=0.044).In the treatment group,the time of body temperature returning to normal [(7.00 ±1.67)d vs. (9.00 ±1.41)d],leukocyte recovery time [(7.83 ±2.32) d vs.(9.82 ±1.94) d],procalcitonin recovery time [(7.00 ±1.67)d vs.(9.00 ±1.41)d],symptom disappearance time [(5.17 ±1.72)d vs.(7.50 ±1.87)d],disap-pearance time of abscess[(12.00 ±3.41)d vs.(16.00 ±2.37)d]were shorter than those in the control group(t=-2.601,-2.890,-2.236,-2.248,-2.362,P=0.026,0.016,0.049,0.044,0.041).Conclusion Venenum bufonis combined with antibiotics can significantly increase the curative rate and accelerate infection control , there-fore,it is worthy of popularizing in clinical practice .
