Clostridium perfringens bacteremia with malignant hematopathy:a case report and review of literatures
10.3969/j.issn.1671-9638.2018.03.019
- VernacularTitle:恶性血液病患者合并产气荚膜梭菌血症1例病例报告并文献回顾
- Author:
Chun-Hui XU
1
;
Yang SU
;
Zhi-Ying TIAN
;
Yan-Xia LV
;
Fu-Jun SUN
;
Dong SU
;
Qing-Song LIN
Author Information
1. 中国医学科学院血液病医院 血液学研究所
- Keywords:
hematopathy;
Clostridium perfringens;
bacteremia;
agranulocytosis
- From:
Chinese Journal of Infection Control
2018;17(3):270-272
- CountryChina
- Language:Chinese
-
Abstract:
Infection is an important cause of higher mortality in patients with hematological diseases than healthy people, and fever is often the only indication of the disease.Clostridium perfringens(C.perfringens)is a grampositive anaerobic bacillus of the Clostridiumgenus, it belongs to the normal flora of the intestinal tract and is not pathogenic in normal condition.However, when intestinal flora is imbalanced due to low hypoimmunity of human body or influenced by such factors as diet, medicine, environment and other factors, it can enter the blood and cause bacteremia.At present, it has never been reported that bacteremia was caused by C.perfringens in patients with malignant hematological diseases accompanied by neutropenia, this article reported the diagnosis and treatment of C. perfringens bloodstream in one patient with malignant hematopathy, so as to provide basis for diagnosis and treatment of the disease.