Analysis of selenium content in hair samples of children in Kashin-Beck disease areas in Shaanxi Province in 2016
10.3760/cma.j.issn.2095-4255.2018.11.007
- VernacularTitle:2016年陕西省大骨节病病区儿童发硒含量的监测
- Author:
Xiaodong YANG
1
;
Hongxing DAI
Author Information
1. 陕西省地方病防治研究所实验室
- Keywords:
Kashin-Beck disease;
Child;
Hair;
Selenium;
Survey
- From:
Chinese Journal of Endemiology
2018;37(11):886-888
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand selenium content in hair samples of children in Kashin-Beck diseased and non-disease areas in Shaanxi Province,and to provide decision-making basis for prevention and treatment of Kashin-Beck disease.Methods In July 2016,two history serious diseased areas Linyou County and Yongshou County were selected as monitoring counties in Shaanxi Province;Fengxiang County and Liquan County were selected as non-disease monitoring counties.According to stratified random sampling,in the 7-12 year old resident children at each monitoring county,5 males and 5 females were taken from each age group,and their hair samples were collected.Samples were digested by wet digestion method,the contents of selenium were determined by 2,3-diaminonaphthalene fluorescence method.Judging criteria:selenium content ＜ 0.20 mg/kg was a selenium deficiency,0.20-＜ 0.25 mg/kg was a selenium edge deficiency,0.25-＜ 0.50 mg/kg was a selenium nutrient medium level,≥0.50 mg/kg is a selenium nutrient high level.Results A total of 240 hair samples were collected,120 cases in the diseased and non-diseased areas,respectively.The selenium contents of children in the diseased and non-disease areas was (0.28 ± 0.13),(0.33 ± 0.13) mg/kg,and the means were between 0.25-＜ 0.50 mg/kg.There was no significant difference in the selenium content in the children between diseased and non-disease areas (t =2.753,P ＞ 0.05).In diseased and non-disease areas,there were 36 and 20 children with selenium content ＜ 0.20 mg/kg,accounting for 30.00％ and 16.67％;15 and 11 children with selenium content 0.20-＜ 0.25 mg/kg,accounting for 12.50％o and 9.17％;61 and 75 children with selenium content 0.25-＜ 0.50 mg/kg,accounting for 50.83％ and 62.50％;8 and 14 children with selenium content ≥0.50 mg/kg,accounting for 6.67％ and 11.67％.There were no significant differences in the selenium contents of hair in boys [(0.27 ± 0.13),(0.33 ± 0.12) mg/kg] and girls [(0.30 ± 0.13),(0.33 ± 0.13) mg/kg] between diseased and non-disease areas (t =2.793,1.219,P ＞ 0.05).Conclusions The selenium contents of children of Kashin-Beck diseased areas in Shaanxi Province are close to the levels of selenium in non-disease areas,and most children are in the medium or high levels of selenium.
