Progression of inflammatory factors IL-1β and TNF-α in Kashin-Beck disease
10.3760/cma.j.issn.2095-4255.2018.09.019
- VernacularTitle:炎性细胞因子白细胞介素-1β和肿瘤坏死因子-α与大骨节病关系的研究进展
- Author:
Zhijun ZHAO
1
;
Qiang LI
;
Daozhong LIU
;
Xin ZHOU
Author Information
1. 青海省地方病预防控制所地方病预防控制科
- Keywords:
Kashin-Beck disease;
Interleukin-1β;
Tumor necrosis factor-α
- From:
Chinese Journal of Endemiology
2018;37(9):769-771
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory factor can cause tissue and cell damage and induce inflammatory reaction,such as production of interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α).Many studies have found that there was a close relationship between the two factors and Kashin-Beck disease (KBD) cartilage damage.The research on TNF-α and IL-1β could help probing the inflammatory reaction during KBD development and occurrence,and finding the interaction between environmental risk factors and environmental reaction gene and protein,then finding effective gene,protein and pathway for KBD prevention and control.
