A comparative study on gene expression profiles and noncoding RNAs regulation between Keshan disease and dilated cardiomyopathy: a recent advance
10.3760/cma.j.issn.2095-4255.2018.07.019
- VernacularTitle:克山病与扩张型心肌病基因表达与非编码RNA调控对比研究进展
- Author:
Guangyong HUANG
1
;
Youzhang XIANG
Author Information
1. 山东大学附属聊城人民医院心内科
- Keywords:
Keshan disease;
Dilated cardiomyopathy;
Gene expression;
Micro RNAs;
Long noncoding RNAs
- From:
Chinese Journal of Endemiology
2018;37(7):595-598
- CountryChina
- Language:Chinese
-
Abstract:
The problem of Keshan disease (KD) is confused with dilated cardiomyopathy (DCM) is still not solved.KD and DCM have different gene expression profiles,namely,different Micro RNAs (miRNAs) and Long noncoding RNAs (lncRNAs).There may be characteristic miRNAs and lncRNAs in KD and DCM.Systemically study differential gene expression profiles and regulation of noncoding RNAs gene expression and elucidate the different molecular pathogenesis in gene expression and gene expression regulation will provide theoretic basis in identification,prevention and treatment of KD and DCM.
