The role of microRNA-140 in the development of osteoarthritis and its important target genes
10.3760/cma.j.issn.2095-4255.2018.05.018
- VernacularTitle:微小RNA-140在骨关节病发生中的作用及其重要的靶基因
- Author:
Bingyu SUN
1
;
Fuyuan LI
;
Ning ZOU
;
Dianjun SUN
Author Information
1. 哈尔滨医科大学中国疾病预防控制中心地方病控制中心地氟病防治研究所国家卫生计生委病因流行病学重点实验室黑龙江省普通高校病因流行病学重点实验室
- Keywords:
microRNA-140;
Target genes;
Osteoarthritis;
Cartilage injury
- From:
Chinese Journal of Endemiology
2018;37(5):426-430
- CountryChina
- Language:Chinese
-
Abstract:
Osteoarthritis is a kind of joint disease with cartilage injury as the main pathological changes.There is no effective treatment for them.With the discovery,research and application of microRNA (miR),it also provides new hope for the treatment of osteoarthropathy.At present,the role of miR in the pathogenesis of cartilage injury has been fully recognized.In this paper,we reviewed the role of miR-140 in the development of osteoarthritis and its important target genes in recent years.
