Clinical features of 99 cases of brucellosis in Henan Province
10.3760/cma.j.issn.2095-4255.2018.05.013
- VernacularTitle:河南省99例布鲁菌病患者临床特征分析
- Author:
Hua LI
1
;
Zhiwei ZHANG
;
Xiaojuan GAO
;
Zujiang YU
;
Zhiqin LI
;
Shuhuan WU
;
Jingjun AN
Author Information
1. 郑州大学第一附属医院感染科
- Keywords:
Brucellosis;
Clinical features;
Therapy regimen
- From:
Chinese Journal of Endemiology
2018;37(5):402-405
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical data of brucellosis,and to provide references for brucellosis therapy.Methods The patients definitely diagnosed brucellosis at the First Affiliated Hospital of Zhengzhou University from January 2013 to June 2016 were assessed,data of clinical features,laboratory examination,treatment and prognosis were analyzed.Results Of all 99 cases,the mean age was (46.7 ± 15.7) years old,83 cases had a history of closely contacted with sheep,2 cases with pig and 1 case with cattle.The occupational distribution of patients included 90 farmers,1 veterinarian,2 cooks,6 children and students.All patients had clinical manifestations such as fever,fatigue,and sweating.There were 18 patients with back and joint pain,13 cases had abnormal manifestation on magnetic resonance imaging (MRI).Blood culture was positive in 54 (71.05％,54/76) and serum test tube agglutination test was positive in 61 (98.39％,61/62).Eighty-one patients received doxycycline combined with rifampicin treatment,six months laters,all patients were cured.Conclusions Sheep are the main sources of infection for brucellosis.Fatigue,sweaty and fever are the most common symptoms,and osteoarticular is the most frequently involved.Serum agglutination test and blood culture are important tests for diagnosis of brucellosis.Doxycycline combined with rifampicin was the most common used antibiotics regimen.Early,combined,regular,full-course antibiotic treatment has a better prognosis.
