Research progress in the relationship between arsenic exposure and glucose and lipid metabolism
10.3760/cma.j.issn.2095-4255.2018.02.020
- VernacularTitle:砷暴露与糖、脂代谢关系的研究进展
- Author:
Xuanbo SONG
1
;
Lijun ZHAO
;
Yudan WEI
Author Information
1. 哈尔滨医科大学中国疾病预防控制中心地氟病防治研究所 国家卫生计生委病因流行病学重点实验室(23618504)黑龙江省普通高校病因流行病学重点实验室
- Keywords:
Arsenic poisoning;
Diabetes mellitus;
Cardiovascular disease;
Glycolipid metabolism
- From:
Chinese Journal of Endemiology
2018;37(2):165-168
- CountryChina
- Language:Chinese
-
Abstract:
Inorganic arsenic is an environmental carcinogen.Chronic exposure to inorganic arsenic has also been suggested being associated with diabetes mellitus and cardiovascular disease, which is a prominent feature of glycolipid metabolism disorders. This article describes the current findings from epidemiological studies on arsenic exposure and diabetes and cardiovascular disease, as well as the possible mechanisms underlying the regulation of glycolipid metabolism after arsenic exposure. It is demonstrated that the effect of arsenic exposure on glycolipid metabolism is mediated through multiple mechanisms that are interrelated, rather than by a single mechanism, eventually leading to diabetes mellitus and cardiovascular disease.
