Skin lesions caused by endemic arsenicosis and pathogenesis: a review
10.3760/cma.j.issn.2095-4255.2018.02.019
- VernacularTitle:地方性砷中毒所致皮肤损伤及其发病机制研究进展
- Author:
Jinyin YAO
1
;
Zhongzhe LI
;
Lin GAO
;
Jing WANG
Author Information
1. 哈尔滨医科大学中国疾病预防控制中心地方病控制中心中心实验室
- Keywords:
Endemic arsenicosis;
Skin;
Pathogenesis
- From:
Chinese Journal of Endemiology
2018;37(2):160-164
- CountryChina
- Language:Chinese
-
Abstract:
Endemic arsenicosis is a kind of endemic diseases, which is caused by chronic arsenic exposure and is seriously harmful to human health. Skin is the important target organ of endemic arsenicosis. Clinical diagnosis for this endemic disease mainly depends on the cutaneous triad (hyperkeratosis on the palms and soles, cutaneous hyper-pigmentation and hypo-pigmentation).But the pathogenesis of this disease is still unclear.In-depth understanding of the skin lesions and the pathogenesis is greatly significant for the scientific explanation of endemic arsenicosis. Although there are some studies on the skin lesions caused by endemic arsenicosis, a systematic review is still lacking. In this paper, the epidemiology, pathological changes and pathogenesis of skin lesions caused by endemic arsenicosis are summarized. Here we expect this summarization will deepen the understanding on skin lesions caused by endemic arsenicosis and provide some new ideas and clues for other researchers.
