Progress on role of CCN1 in pulmonary diseases
10.3969/j.issn.1000-4718.2018.01.033
- VernacularTitle:基质蛋白CCN1与肺部疾病的研究进展
- Author:
Nian DONG
1
;
Chen-Jian SONG
;
Dan-Ping QIU
;
Cheng-Shui CHEN
Author Information
1. 温州医科大学附属第一医院呼吸与危重症医学科
- Keywords:
CCN1;
Acute lung injury;
Chronic obstructive pulmonary disease;
Lung cancer
- From:
Chinese Journal of Pathophysiology
2018;34(1):188-192
- CountryChina
- Language:Chinese
-
Abstract:
Cysteine-rich angiogenic inducer 61(Cyr61/CCN1)is an extracellular matrix-associated signaling protein consisting of 381 amino-acid residues ,which has the regulatory function for a multitude of cellular responses.The pleiotropic effects of CCN 1 on the initiation and resolution of inflammation as well as oncogenesis and development of tumor were reported.According to the numerous data from experimental and clinical studies ,this article provides an overview on CCN1 and summarizes the latest understanding of the role of CCN 1 in pulmonary diseases.
