Three Cases of Skin Pigmentation Caused by 2,5-Hexanedione.
- Author:
Seong Ah KIM
1
;
Sang Jae JUNG
;
Chae Yong LEE
;
Sang Man LEE
;
Sang Woo KIM
Author Information
1. Department of Occupational and Environmental Medicine, Kumi CHA Hospital, and Pochun CHA University, Korea. drsakim@hanmail.net
- Publication Type:Case Report
- Keywords:
Skin pigmentation;
2,5-Hexanedione;
Surveillance
- MeSH:
Gyeongsangbuk-do;
Occupational Diseases;
Physical Examination;
Skin Pigmentation*;
Skin*
- From:Korean Journal of Occupational and Environmental Medicine
2002;14(2):199-203
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: To report on the skin discoloration experienced by three workers handling 2 , 5 -hexanedione METHODS: Three workers, who showed orange-brown discoloration of the palms during observation under the Kumi occupational disease surveillance system, had their history evaluated and underwent physical examination. A workplace survey was performed by an occupational physician and an industrial hygienist. RESULTS: The three workers were determined to have been experiencing skin discoloration since the introduction of a new cleaning solvent. The new solvent contained 2,5-hexanedione, which is reported in the literature to be possibly capable of causing orangebrown discoloration of the skin. After discontinuation of solvent use, the workers recovered within a week. CONCLUSIONS: These cases demonstrate that 2,5-hexanedione can produce skin pigmentation.
