Quality Standard of Huangqi Baoxin Mixture
10.3870/j.issn.1004-0781.2018.03.017
- VernacularTitle:黄芪保心合剂质量标准
- Author:
Wei WU
1
;
Peiying ZHANG
;
Yonggang CHEN
;
Xingjie CHANG
;
Shiqiang WU
;
Jiayu ZHANG
Author Information
1. 南京中医药大学
- Keywords:
Huangqi baoxin mixture;
Quality standard;
Chromatography;
thin-layer;
Scattering detection;
High perform-ance liquid chromatography-evaporative light
- From:
Herald of Medicine
2018;37(3):341-344
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a quality standard of huangqi baoxin mixture and improve its quality control system. Methods The qualitative analysis of Astragalus membranaceus,Salvia miltiorrhiza,Forsythia,and Angelica were performed by TLC.The content determination of astragalosideⅣin the huangqi baoxin mixture was conducted by HPLC-ELSD. Results As-tragalus membranaceus,Salvia miltiorrhiza,Forsythia,and Angelica in the huangqi baoxin mixture could be accurately identified by TLC.The linear range of astragaloside Ⅳ was 1.224-10.20 μg (r=0.999 5).RSDs of precision,stability,and reproducibility tests were lower than 3.0%;the recovery was 96.2%-102.9% with RSD at 2.20% (n=6). Conclusion The established quan-titative method is simple,accurate,and reliable with high specificity which can be used to control the quality of huangqi baoxin mixture.
