Serum Peroxiredoxin 3 in Early Pregnant Women

VernacularTitle:过氧化物还原酶3在早孕妇女血清中的水平
Author: Lei SUI ^{1
,

2} ; Aihua LIANG ; Lianqin LI
Author Information

1. 264003烟台,滨州医学院
2. 252000 聊城市第四人民医院妇科
Keywords: Peroxiredoxin; Pregnancy; Reactive oxygen species; Oxidative stress
From: Journal of Medical Research 2018;47(1):108-110
CountryChina
Language:Chinese
Abstract: Objective To investigate the role of peroxiredoxin 3 (PRX3) in early pregnancy.Methods We collected serum and villus tissues from ninety patients at first trimester.Enzyme-linked immunosorbent assay,real-time PCR,and Western Blotting were applied to examine the PRX3 level in above samples.Results The serum PRX3 in pregnant women was significantly higher than in non -pregnant controls.The expression of PRX3 in villus tissues was increased with gestational progression.Conclusion The oxidative stress was increased in pregnant women.PRX2 plays an active role in antioxidant defense of villus tissues.