A Case of Polio-like Encephalomyelitis Associated with Enterovirus 71 Infection.
- Author:
Hyun Kyung ROH
1
;
Hee Jung CHUNG
;
Young Mee JEE
;
Doo Sung CHEON
Author Information
1. Department of Pediatrics, College of Medicine, Yonsei University, Seoul, Korea. agathac@NHIMC.or.kr
- Publication Type:Case Report
- Keywords:
Enterovirus 71;
Polio-like encephalomyelitis;
Serious CNS complications
- MeSH:
Animals;
Australia;
Brain;
Brain Stem;
Bulgaria;
California;
Central Nervous System;
Child;
Diagnosis;
Disease Outbreaks;
Encephalitis;
Encephalomyelitis*;
Enterovirus*;
Feces;
Female;
Follow-Up Studies;
Horns;
Humans;
Hungary;
Infant;
Magnetic Resonance Imaging;
Medulla Oblongata;
Meningitis;
Meningitis, Aseptic;
Myelitis;
Paralysis;
Poliovirus;
Spinal Cord;
Sweden
- From:Journal of the Korean Pediatric Society
2001;44(11):1305-1310
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Enterovirus 71(EV71), like polioviruses, invades the central nervous system to give rise to aseptic meningitis, encephalitis or myelitis. EV71 was first isolated in California in 1969 from a 9-month- old infant with encephalitis. Since then it has been isolated from the brain of children who died of encephalitis and from feces of patients with meningitis, encephalitis or paralysis. Related strains have been isolated from outbreaks of similar diseases in Australia, Sweden, Bulgaria and Hungary. We have experienced polio-like encephalomyelitis in a 3-month-old girl. Initial brain MR imaging showed tissue destruction in the bilateral posterior portions of the medulla oblongata and the bilateral anterior horns of cervical spinal cord from C3 to C6 level. Follow-up MR imaging was performed 3 months later, which showed minimal residual change on the anterior horn of the cervical spinal cord at C4 level only. This report deals with rare polio-like encephalomyelitis associated with EV71 and discusses its diagnosis and management. Brain stem and cervical spinal cord involvement are characteristic findings of EV encephalomyelitis.
