The research progress of the correlation between vitamin D deficiency and coronary atherosclerotic heart disease
10.3760/cma.j.issn.1673-4904.2018.11.024
- VernacularTitle:维生素D缺乏与冠状动脉粥样硬化性心脏病的相关性研究进展
- Author:
Mengying LUO
1
;
Deling ZOU
Author Information
1. 中国医科大学附属盛京医院第三心血管内科
- Keywords:
Coronary artery disease;
Vitamin D deficiency;
Inflammation;
Endothelial Cells;
Review
- From:
Chinese Journal of Postgraduates of Medicine
2018;41(11):1053-1056
- CountryChina
- Language:Chinese
-
Abstract:
Vitamin D is an important organic substance in the body to maintain the balance of calcium and phosphorus, and it is also closely related to the occurrence and development of coronary atherosclerotic heart disease (referred to as coronary heart disease). Vitamin D deficiency can lead to the occurrence of coronary heart disease by activating the inflammatory response, weakening the protective effect of the vascular endothelium, activating the renin-angiotensin-aldosterone system, impairing insulin function, triggering abnormal glucose and lipid metabolism, and increasing body weight. The effect of vitamin D supplementation on coronary heart disease still requires large-scale clinical trials to confirm.
