Mechanism research progress of iron removal by eltrombopag
10.3760/cma.j.issn.1673-4904.2018.11.022
- VernacularTitle:艾曲波帕去铁机制研究进展
- Author:
Dongfeng MAO
1
;
Tao WU
;
Honggang CAO
;
Hai BAI
Author Information
1. 730050,兰州军区兰州总医院全军血液病中心
- Keywords:
Iron metabolism disorders;
Receptors,thrombopoietin;
Review;
Eltrombopag
- From:
Chinese Journal of Postgraduates of Medicine
2018;41(11):1046-1048
- CountryChina
- Language:Chinese
-
Abstract:
Eltrombopag is a kind of human thrombopoietin receptor agonist, which is used to treat thrombocytopenia and severe aplastic anemia. In recent years, it highlights the huge advantage in iron removal. It regulates the acidification of glucuronidation in the body, removing it from feces and urine before iron conjugates to the liver, so as to effectively reduce the overload of iron in the body.
