Progress in studies on the role of mitochondria in vascular calcification
10.3760/cma.j.issn.1673-4904.2018.10.022
- VernacularTitle:线粒体在血管钙化中的作用研究进展
- Author:
Qing ZHANG
1
;
Shipeng YU
Author Information
1. 272000,济宁医学院
- Keywords:
Mitochondria;
Vascular calcification;
Oxidative stress;
Autophagy;
Apoptosis;
Review
- From:
Chinese Journal of Postgraduates of Medicine
2018;41(10):953-956
- CountryChina
- Language:Chinese
-
Abstract:
Vascular calcification is a complex pathological process involving multiple factors.The latest research has confirmed that mitochondria plays an important role in the process of vascular calcification. Inorganic phosphate treatment, oxidative stress, autophagy, apoptosis, power related protein, mitochondrial DNA damage can affect the process of changing the calcification of the arterial by affecting mitochondrial function. So we will review the role of mitochondria in vascular calcification, further study the molecular mechanism of vascular calcification, and provide a theoretical basis for the formulation of new treatment strategies.