γδ T cells and cancer immunotherapy
10.3760/cma.j.issn.1673-4904.2018.07.020
- VernacularTitle:γδT细胞与肿瘤免疫治疗
- Author:
Yuwei ZHAO
1
;
Xiongfei WU
;
Lijuan ZOU
;
Xiaoying XU
Author Information
1. 116023,大连医科大学附属第二医院肿瘤放疗科
- Keywords:
T-lymphocytes;
Antineoplastic protocols;
Immunotherapy;
Review
- From:
Chinese Journal of Postgraduates of Medicine
2018;41(7):659-664
- CountryChina
- Language:Chinese
-
Abstract:
γδ T cells have been well recognized as a unique cell population that is actively involved in both innate and adoptive immunity of bodies. The features of γδ T cells, such as their major histocompatibility complex independent antigen recognition and their cytotoxic effects to tumor cells, make them as promising candidates used for cancer immunotherapy. There is a strong interest in developing γδ T cell-based immunotherapy for clinical application in treating cancer patients. This review discusses the progress of recent studies related to the γδ T cells and cancer immunotherapy, with an emphasis on the main characteristics of γδ T cells in several types of gynecologic tumors.
