Effect of transcranial direct current combined with mirror neuronal rehabilitation training
10.3760/cma.j.issn.1673-4904.2018.07.004
- VernacularTitle:经颅直流电刺激联合镜像神经元康复训练系统对重型颅脑损伤后意识障碍患者的疗效
- Author:
Yabin LI
1
;
Haixia FENG
;
Jiao LI
;
Hongxia WANG
;
Xiaohong QIAO
;
Zhongrui MA
;
Ning CHEN
;
Yanchen WANG
;
Aiqiang BAO
;
Liyuan HAN
;
Dang WEI
Author Information
1. 甘肃省康复中心医院神经康复科
- Keywords:
Craniocerebral trauma;
Electric stimulation therapy;
Rehabilitation;
Consciousness disorders
- From:
Chinese Journal of Postgraduates of Medicine
2018;41(7):589-593
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of transcranial direct current stimulation (tDCS) with mirror neuronal rehabilitation training system (MNST-V1.0) in post-traumatic unconscious patients after severe craniocerebral injury. Methods A prospective, self controlled and open-label method was used. Thirty-six post-traumatic unconscious patients with severe craniocerebral injury from January 2016 to July 2017 were selected. Four cases of the patients did not complete the treatment and the last 32 cases completed the study. All patients were given routine wake-up therapy, and tDCS combined with MNST-V1.0 (20 min/time, 1 time/d, 6 times/week, a total of 8 weeks) was given at the same time. The Glasgow coma scale (GCS), JFK coma recovery scale and Four coma rating scale before treatment and 2, 4, 8 weeks after treatment were recorded. Results The scores of open reaction, language and motor response score of GCS 2, 4, 8 weeks after treatment were significantly higher than those before treatment:(1.56 ± 0.82), (2.06 ± 1.01) and (3.11 ± 1.45) scores vs. (1.00 ± 0.45) scores, (2.23 ± 1.06), (2.56 ± 1.08) and (3.02 ± 1.04) scores vs. (1.00 ± 0.61) scores, (2.79 ± 1.12), (3.22 ± 1.33) and (4.44 ± 1.07) scores vs. (1.00 ± 0.54) scores, and there were statistical differences (P ＜ 0.01 or ＜0.05). The scores of hearing, vision, movement, speech response, communication and arousal of JFK coma recovery scale 2, 4, 8 weeks after treatment were significantly higher than those before treatment, and there were statistical differences (P＜0.01). The scores of open reaction, sport reaction, brainstem response of Four coma rating scale 2, 4, 8 weeks after treatment were significantly higher than those before treatment, and there were statistical differences (P＜0.05); there was no statistical difference in respiratory score of Four coma rating scale before and after treatment (P＞0.05). Conclusions The tDCS combined with MNST-V1.0 can improve the consciousness level in post-traumatic unconscious patients with severe craniocerebral injury, and have the effect of promoting awakening.
