Investigation of prevalence and risk factors of H-type hypertension among middle-aged and elderly people in Beijing community
10.3760/cma.j.issn.1673-4904.2018.05.016
- VernacularTitle:北京社区中老年人H型高血压患病率及其危险因素分析
- Author:
Zhongying ZHANG
1
;
Xianghua FANG
;
Xunming JI
;
Zhe TANG
;
Chunxiu WANG
;
Hongjuan QIAN
;
Shaochen GUAN
;
Hongjun LIU
;
Xiaoguang WU
;
Chengbei HOU
;
Xiang GU
Author Information
1. 首都医科大学宣武医院综合科
- Keywords:
Hypertension;
Middle aged;
Aged;
Prevalence;
Risk factors
- From:
Chinese Journal of Postgraduates of Medicine
2018;41(5):443-448
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence and risk factors of H-type hypertension among middle-aged and elderly people in Beijing community. Methods A cross-sectional study by recruiting 1 458 middle-aged and elderly people from a cohort of the "Beijing Longitudinal Study of Aging" in 2009 was conducted. All participants were asked to complete a standardized questionnaire, physical examination and laboratory examinations. Hyperhomocysteinemia was defined as homocysteine (Hcy) > 15 μmol/L, and H- type hypertension was defined as having hypertension and hyperhomocysteinemia simultaneously. The prevalence of H-type hypertension was estimated by using the results of 2000 Beijing population census to weight the data. Multivariate Logistic regression analysis was preformed to estimate the associated factors of H-type hypertension. Results The age was (69.48 ± 8.09) years, and the distribution of Hcy was skewed with the median of 16.56 μmol/L. After weight, the prevalence of hyperhomocysteinemia was 57.20% (834/1 458), and the prevalence of H-type hypertension was 35.32% (515/1 458), accounting for 59.47% (515/866) in patients with hypertension. The ageing, male, hyperuricemia, estimated glomerular filtration rate (eGFR) and insufficiency of fishes/ shrimps were independent risk factors of H-type hypertension ( OR = 2.30, 1.04, 1.02, 0.95 and 0.67; 95% CI 1.54-3.44, 1.02-1.06, 1.04-1.06, 0.94-0.97 and 0.46-0.97; P＜0.01 or＜0.05). Conclusions The proportion of H-type hypertension is high in the middle-aged and elderly people in Beijing community. Lowering uric acid, protection of renal function and intake sufficient fishes and shrimps might prevent and control H-type hypertension.
