Effects of low frequency pulsed electromagnetic field on stomach blood circulation and ultra microstructure of stress ulcer in rats
10.7687/j.issn1003-8868.2018.05.035
- VernacularTitle:低频脉冲电磁场对大鼠应激性溃疡胃壁血液循环及超微结构的影响
- Author:
Ming-Ke JIAO
1
;
Fang-Li WANG
;
Jie HU
;
Lin JIAO
;
Peng ZHANG
Author Information
1. 新疆军区总医院医学工程科
- Keywords:
low frequency pulsed electromagnetic field;
stress ulcer;
blood circulation;
ultra microstructure
- From:
Chinese Medical Equipment Journal
2018;39(5):35-38
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine non-thermal biological effect of low frequency pulsed electromagnetic field (LFPEF)on the stomach blood circulation and ultra microstructure of rat stress ulcer. Methods Thirty-six Sprague-Dawley rats were assigned to three equal groups:control,ulcer without interference group(UW)and ulcer exposure groups(UE).The rats stress ulcer models were constructed with the combination method of soak and bind in the low-pressure and hypoxia circumstance. Based on the singlechip,a LFPEF generator with adjustable frequency, amplitude and duty ratio was developed. Then the stomachs of the rats were exposed to the LFPEF generator 3 hours per day.On days 1,3,5 and 7,the blood circulation of the stomach was analyzed by the content of the serum NO and contrast ultrasonography.In addition,the ulcer tissue was taken out for section-staining. Finally, the pathological change of the stomach ultra microstructure was observed under a light microscope. Results On different days, the contents of the serum NO and microbubble concentration of UE group were significantly higher than those of the UW group(P<0.05). The pathological observation showed that the restoration of the gastric tissue in UE group was faster than that in the UW group(P<0.05).Conclusion LFPEF with certain proper parameter could improve the gastric tissue blood circulation and accelerate the stress ulcer restoration. [Chinese Medical Equipment Journal,2018,39(5):35-38]
