Study of laser speckle blood flow imaging based on de-correlation algorithm
10.7687/j.issn1003-8868.2017.12.001
- VernacularTitle:基于去相关算法的激光散斑血流成像研究
- Author:
Yi-Lu LI
1
;
Li-Wei WANG
;
Kai-Ning LI
;
Yue-Jie LI
Author Information
1. 中国医学科学院北京协和医学院生物医学工程研究所
- Keywords:
de-correlation algorithm;
laser speckle;
speckle image;
blood flow imaging;
cross-correlation
- From:
Chinese Medical Equipment Journal
2017;38(12):1-4,19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application of de-correlation algorithm to laser speckle blood flow imaging technique and study the blood flow velocity.Methods The principle and algorithm were analyzed for de-correlation laser speckle blood flow imaging.A laser speckle imaging platform was established,and de-correlation laser speckle blood flow imaging algorithm was used to execute microfluidic target experiment and animal experiment.De-correlation algorithm was applied to obtaining blood flow image and velocity curve of microfluidic target.Cross-correlation curve on the original speckle images were got with cross-correlation algorithm,and the original images corresponding to the peak points were selected to undergo computation with de-correlation algorithm,so that the minute information could be augmented on the blood vessel.Results The de-correlation laser speckle blood flow imaging algorithm could be used to obtain the blood flow information and velocity information during microfluidic target experiment and the animal experiment.Conclusion The de-correlation laser speckle blood flow imaging algorithm is feasible in laser speckle imaging,and has good application prospects.