Association of anterior chamber angle open parameters with postoperative intraocular pressure following laser peripheral iridotomy
10.3760/cma.j.issn.2095-0160.2018.04.013
- VernacularTitle:激光虹膜周边切除术后前房角测量参数变化与术后眼压的关系
- Author:
Qian LIU
1
;
Yangzeng DONG
;
Haijun LI
;
Yingfei WANG
;
Yalin HUANG
;
Liang DONG
;
Changgeng LIU
Author Information
1. 450003,河南省立眼科医院河南省眼科研究所河南省人民医院郑州大学人民医院眼科
- Keywords:
Ultrasound biomicroscopy;
Biometry;
Anterior chamber;
Ocular hypertension/surgery;
Laser/treatment use;
Laser peripheral iridomtomy;
Retrospective study
- From:
Chinese Journal of Experimental Ophthalmology
2018;36(4):289-293
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the relationship between anterior chamber angle and intraocular pressure (IOP) after laser peripheral iridotomy (LPI) treatment.Methods A retrospective cases control study was adopted.Fifty-eight patients (58 eyes) who were diagnosed as primary angle closure (PAC) were included in this study.Ultrasound biomicroscopy (UBM) parameters in angle opening distance (AOD),trabecular iris area (TISA) and angle recess area (ARA) examination were performed before LPI.The changes of intraocular pressure (IOP) were compared between different time-points (before and 1 hour,2 hours,8 hours,24 hours,2 weeks,6 months and 12 months after LPI).The patients were divided into IOP≤21 mmHg group (41 eyes) and IOP＞21 mmHg group (17 eyes) after LPI.Relationship between anterior chamber angle and IOP after LPI treatment was explored.This study was approved by Ethic Committee of the Henan Eye Institute and informed consent was obtained from each patient.Results The IOPs were increased in 1 hour,2 hours after LPI and lowered in 2 weeks,6 months,12 months after LPI compared with IOP before LPI,with significant differences between them (all at P＜0.01).Twelve patients suffered transient elevated IOP and recovered by self-healing or treatment.IOP of 4 patients were elevated after 6 months to 1 year follow-up.The IOPs in 2 weeks,6 months and 12 months after LPI were lowered compared with IOP before LPI,with significant differences between them (all at P＜0.01).The UBM parameters were significantly increased in 2 weeks,6 months,12 months after LPI in comparison with IOP before IPL (all at P＜0.01).IOP and UBM parameters values were significantly different between IOP＞21 mmHg group and ≤21 mmHg group after LPI.Regression analysis indicated that ARA750 (OR =0.75,P＜0.05) was correlated to the IOP after LPI rather than IOP before operation,AOD and TISA (P＞0.05).Conclusions ARA750 value is correlated with the IOP variations after LPI.UBM structured observation can improve the surgical successful rates and safty and prevent complications.
