Paying attention to the prognosis guiding effects of CNV dynamic changes based-OCT angiography in neovascular age-related macular degeneration after antiangiogenic therapy
10.3760/cma.j.issn.2095-0160.2018.01.001
- VernacularTitle:关注OCT血管成像检测的CNV血管形态特征动态变化对抗VEGF治疗后新生血管性AMD应答反应的预测作用
- Author:
Zhi ZHAO
1
,
2
;
Xiaodong SUN
Author Information
1. 200080 上海交通大学附属第一人民医院眼科 上海市眼底病重点实验室 上海市眼视觉及光医学工程技术研究中心
2. 江苏大学附属人民医院眼科
- Keywords:
Tomography,optical coherence;
Age-related macular degeneration,neovascular/drug therapy;
Choroidal neovascularization/drug therapy;
Prognosis;
Vascular endothelial growth factor;
Optical coherence tomography angiography
- From:
Chinese Journal of Experimental Ophthalmology
2018;36(1):1-4
- CountryChina
- Language:Chinese
-
Abstract:
Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is a first line therapy for neovascular age-related macular degeneration (nAMD).However,how to predict the respond for antiVEGF treatment is still a challenge in clinic practice.Optical coherence tomography angiography (OCTA) can offer dynamic following-up for choroidal neovascularization (CNV) in nAMD after antiangiogenic therapy.The change of vascular morphology based on OCTA enriches the novel theory of prognosis for tveatment of nAMD and can be considered as a biomarker of neovascularization in vivo,which can help us to evaluate the activity of CNV and understand the mechanism of anti-VEGF resistance.So,OCTA should be a standard strategy during the diagnosis,treatment and follow-up of nAMD.We should pay more attention to the guiding significance in the prognosis evaluation of nAMD basis on character of vascular morphology by OCTA following antiangiogenic therapy.
